- The Kingdom was too big to be effectively administered.
- Lack of able leadership especially after the death of Kabaka Muteesa 1 in 1884.
- Attacks from vassal states e.g. Busoga greatly weakened the kingdom.
- Land conflicts with Bunyoro also increased hostilities with her neighbours.
- Internal conflicts especially power struggles led to disunity in the kingdom.
- Disunity because of social classes also weakened her military strength.
- Natural calamities e.g. floods and diseases especially sleeping sickness which killed many people.
- The coming of Missionaries also led to disunity within the kingdom hence her decline.
- The coming of colonialists who effectively led to the loss of her independence.
