- Seme was educated through the mission school up to the university level in U.S.A and Britain.
- He was alarmed by the suffering and humiliation of his fellow Africans
- In 1912 Seme together with others called the conference of all African chiefs and leaders and started the African Native Congress.
- In 1912 still, Seme began the first national African news paper The Abatu –Bathu (‘people’) which was published in English and other three Bantu languages.
- He bought land in eastern Transvaal and set up the African farmer Association in an attempt to promote modern methods of farming
- He was opposed to the militant approach in the demand for African freedoms
- He had difficult in working with others because he always demanded for control.
- His newspaper and the farmers’ association were forced to close soon after a good beginning.
- Seme died in 1951 when the leadership of the A.N.C was already under Dr A B Zulu.